This house, clustered with three others both behind and beside it, was once a part of an exclusive residential neighbourhood. Built for Rupert Simpson, co-owner of the Toronto Knitting and Yarn Factory, the city's first knitting mill, this house and the stable behind it were designed by Toronto architect Charles J. Gibson in the Romanesque Revival style then popular with wealthier Torontonians. In 1922, the home became the convent of the Sisters of Service, the first English-speaking Roman Catholic women's order in Canada. It was subsequently acquired in the late 1960's by Princess Margaret Hospital as a nurses' residence. Retaining elaborate interior features inspired by Queen Anne architecture, the Rupert Simpson house was renovated and restored in 2005.