Born at Prescott, Scott was admitted to the bar in 1848 and practiced law in Ottawa. As a member of the legislature of Upper Canada (1857-63) he sponsored the Separate School Act of 1863. Subsequently, he represented Ottawa in the Ontario legislature (1867-73) and was Commissioner of Crown Lands (1871-3). Appointed to the Senate in 1874, he served as Secretary of State in the Mackenzie Cabinet (1874-8) and was responsible for the Canada Temperance Act of 1878. He held the same post in the Laurier Government (1898-1908), and was Liberal leader in the Senate (1903-8). He died at Ottawa.