Rousseaux was the first European to settle in the Toronto area. He and his father were interpreters for the Indian Department and were licensed to trade in this region. In 1787 Jean-Baptiste married Margaret Clyne, a ward of Mohawk chief Joseph Brant, and by 1791 he had built a trading post here at the Toronto Carrying Place. When Lieutenant-Governor Simcoe arrived by schooner to establish the provincial capital of York in 1793, Rousseaux piloted him into harbour. He served Simcoe's government as an interpreter thereafter. Intent on expanding his business activities, Rousseaux moved to Ancaster in 1795, where he prospered as a merchant and landowner. He fell ill and died while serving at Fort George during the War of 1812.