Once one of the city's largest centres of charity, the House of Providence stood nearby for over 100 years. It was initiated by Toronto's Roman Catholic Bishop, Armand-François-Marie de Charbonnel, in response to the plight of the desperately poor, including many Irish immigrants. To provide shelter and food for those most in need, de Charbonnel enlisted both the help of the Sisters of St. Joseph and the generosity of the surrounding community. Operated by the Sisters, the House of Providence opened in 1857.
Nearly always filled to capacity, the House of Providence would eventually quadruple in size to provide for about 700 residents, including the elderly, the unemployed, orphans, widows, and newcomers to Canada. Some stayed only a few days; others, for years. At its doors, daily meals were given out to the hungry, particularly during the Great Depression of the 1930s.
The House of Providence was demolished in 1962 to make way for the Richmond Street exit from the Don Valley Parkway. It was by then a home for the aged, and its residents moved with the sisters of St. Joseph to Providence Villa and Hospital, a new facility located at St. Clair and Warden Avenues, and known today as Providence Healthcare.