Trinity College Medical School
The Upper Canada School of Medicine was organized in 1850. It became the medical faculty of the University of Trinity College and continued until 1856 when the school was dissolved. Re-established in 1870, this building was erected for medical teaching purposes. It was incorporated as an independent medical school in 1877, becoming Trinity Medical College in 1887. Trinity College granted degrees until 1903, when it federated with the University of Toronto. After 1903 the building was occupied by the Ontario Mattress Company. In 1979 it was converted to residential use.
Plaque via Alan L. Brown's site Toronto Plaques. Full page here.